Synaptophysin anticorps (AA 224-313)

N° du produit ABIN7872388

Cet anticorps anti-Synaptophysin Monoclonal Souris (Clone SYP-3551) (ABIN7872388) détecte spécifiquement Synaptophysin dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Synaptophysin anticorps (AA 224-313) (ABIN7872388)

Antigène: Synaptophysin (SYP)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Synaptophysin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: SYP-3551

Détail du produit anti-Synaptophysin anticorps

Épitope: AA 224-313

Fonction: Synaptophysin Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A recombinant human Synaptophysin protein fragment within amino acids 224-313 was used as the immunogen for the Synaptophysin antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Synaptophysin antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Synaptophysin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Synaptophysin

Antigène: Synaptophysin (SYP)

Autre désignation: Synaptophysin

Sujet: This monospecific monoclonal antibody recognizes a protein of 38 kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity