Recombinant Synaptophysin anticorps (AA 224-313)

N° du produit ABIN7872392

Cet anticorps Souris Monoclonal détecte spécifiquement Synaptophysin dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant Synaptophysin anticorps (AA 224-313) (ABIN7872392)

Antigène: Synaptophysin (SYP)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Synaptophysin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RSYP-8807

Détail du produit anti-Synaptophysin anticorps

Épitope: AA 224-313

Fonction: SYP Antibody / Synaptophysin

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 224-313) from the human protein was used as the immunogen for the SYP antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the SYP antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SYP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Synaptophysin

Antigène: Synaptophysin (SYP)

Autre désignation: SYP

Sujet: This recombinant mouse monoclonal antibody recognizes a protein of 38 kDa that is identified as synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel.This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

UniProt: P08247

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity