MID1 anticorps (AA 226-278)

N° du produit ABIN7872405

L’anticorps anti-MID1 Polyclonal Lapin est utilisé pour la détection de MID1 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IF, IHC (p) et FACS.

Aperçu rapide pour MID1 anticorps (AA 226-278) (ABIN7872405)

Antigène: MID1 (Midline 1 (MID1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MID1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-MID1 anticorps

Épitope: AA 226-278

Fonction: MID1 Antibody

Purification: Affinity purified

Immunogène: Amino acids N226-Q278 from the human protein were used as the immunogen for the MID1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MID1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: Store the MID1 antibody at -20oC.

Détails sur MID1

Antigène: MID1 (Midline 1 (MID1))

Autre désignation: MID1

Sujet: Midline-1 is a protein found in humans that is encoded by the MID1 gene. The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities.

UniProt: O15344