STEAP2 anticorps (AA 229-258)
Aperçu rapide pour STEAP2 anticorps (AA 229-258) (ABIN7872430)
Antigène
Voir toutes STEAP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 229-258
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Fonction
- STEA2 Antibody
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 229-258 from the human protein was used as the immunogen for the STEA2 antibody.
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Isotype
- IgG
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the STEA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the STEA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))
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Autre désignation
- STEA2
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Sujet
- This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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UniProt
- Q8NFT2
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Pathways
- Transition Metal Ion Homeostasis
Antigène
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