Recombinant T-Box 1 anticorps (AA 235-435)

N° du produit ABIN7872616

Cet anticorps anti-T-Box 1 Monoclonal Lapin (Clone TBXT-7711R) (ABIN7872616) détecte spécifiquement T-Box 1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant T-Box 1 anticorps (AA 235-435) (ABIN7872616)

Antigène: T-Box 1 (TBX1)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp T-Box 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TBXT-7711R

Détail du produit anti-T-Box 1 anticorps

Épitope: AA 235-435

Fonction: Brachyury Antibody / TBXT / Protein T

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 235-435) from the human protein was used as the immunogen for the Brachyury antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the Brachyury antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Brachyury antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur T-Box 1

Antigène: T-Box 1 (TBX1)

Autre désignation: Brachyury

Sujet: The T-box gene family consists of members that share a unique DNA binding domain. The best characterized T-box (Tbx) gene, brachyury or T, encodes a transcription factor that plays an important role in early vertebrate development. Tbx genes are a family of developmental regulators with more than 20 members recently identified among invertebrates and vertebrates. Mutations in Tbx genes have been found to cause several human diseases. The understanding of functional mechanisms of Tbx products has come mainly from the prototypical T/brachyury protein, which is a transcription activator. The T-domain is a highly conserved DNA-binding motif originally defined in brachyury and characteristic of the Tbx family of transcription factors. The murine brachyury (T) gene is required in posterior mesoderm formation and axial development. Mutant embryos lacking T gene function are deficient in notochord differentiation and posterior mesoderm formation, but develop anterior mesoderm.

UniProt: O15178

Pathways: Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation