APOA4 anticorps (AA 239-371)
Aperçu rapide pour APOA4 anticorps (AA 239-371) (ABIN7872646)
Antigène
Voir toutes APOA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 239-371
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Fonction
- APOAIV Antibody / Apolipoprotein A4
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Purification
- Protein G affinity chromatography
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Immunogène
- A portion of amino acids 239-371 from the human protein was used as the immunogen for the APOAIV antibody.
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal dilution of the APOAIV antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the APOAIV antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- APOA4 (Apolipoprotein A-IV (APOA4))
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Autre désignation
- APOAIV
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Sujet
- Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA). The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.
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UniProt
- P06727
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Pathways
- Lipid Metabolism
Antigène
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