Desmoglein 2 anticorps (AA 24-1020)

N° du produit ABIN7872660

L’anticorps anti-Desmoglein 2 Monoclonal Souris est utilisé pour la détection de Desmoglein 2 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour Desmoglein 2 anticorps (AA 24-1020) (ABIN7872660)

Antigène: Desmoglein 2 (DSG2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmoglein 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2B4D1

Détail du produit anti-Desmoglein 2 anticorps

Épitope: AA 24-1020

Fonction: DSG2 Antibody / Desmoglein 2

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids L24-E1020) was used as the immunogen for the DSG2 antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the DSG2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the DSG2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Desmoglein 2

Antigène: Desmoglein 2 (DSG2)

Autre désignation: DSG2

Sujet: Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current diagnostic criteria to take account of LV disease, childhood disease expression, and incomplete penetrance.

UniProt: Q14126

Pathways: Cell-Cell Junction Organization