ATR anticorps (AA 24-1324)

N° du produit ABIN7872663

L’anticorps anti-ATR Polyclonal Lapin est utilisé pour la détection de ATR dans des échantillons de Humain. Il a été validé pour ELISA et IF.

Aperçu rapide pour ATR anticorps (AA 24-1324) (ABIN7872663)

Antigène: ATR (ATR serine/threonine kinase (ATR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATR est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Détail du produit anti-ATR anticorps

Épitope: AA 24-1324

Fonction: ATR Antibody / Ataxia telangiectasia and Rad3-related protein / FRP1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids E24-D1324) was used as the immunogen for the ATR antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the ATR antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the ATR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ATR

Antigène: ATR (ATR serine/threonine kinase (ATR))

Autre désignation: ATR

Sujet: Serine/threonine-protein kinase ATR also known as ataxia telangiectasia and Rad3-related protein (ATR) or FRAP-related protein 1 (FRP1) is an enzyme that, in humans, is encoded by the ATR gene. The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

UniProt: Q13535

Pathways: Positive Regulation of Response to DNA Damage Stimulus