AANAT anticorps (AA 24-205)

N° du produit ABIN7872672

L’anticorps anti-AANAT Polyclonal Lapin est utilisé pour la détection de AANAT dans des échantillons de Souris. Il a été validé pour ELISA et WB.

Aperçu rapide pour AANAT anticorps (AA 24-205) (ABIN7872672)

Antigène: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AANAT est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-AANAT anticorps

Épitope: AA 24-205

Fonction: Aanat Antibody

Purification: Antigen affinity purified

Immunogène: Recombinant mouse Aanat protein (amino acids C24-C205) was used as the immunogen for the Aanat antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Aanat antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Aanat antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur AANAT

Antigène: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Autre désignation: Aanat

Sujet: Aralkylamine N-acetyltransferase (AANAT) (EC 2.3.1.87), also known as arylalkylamine N-acetyltransferase or serotonin N-acetyltransferase (SNAT), is an enzyme that is involved in the day/night rhythmic production of melatonin, by modification of serotonin. It is in humans encoded by the ~2.5 kb AANAT gene containing four exons, located on chromosome 17q25. The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternative splicing results in multiple transcript variants.

UniProt: O88816

Pathways: Photoperiodism