STRADB anticorps (AA 24-411)

N° du produit ABIN7872690

L’anticorps anti-STRADB Polyclonal Lapin est utilisé pour la détection de STRADB dans des échantillons de Humain. Il a été validé pour WB, ELISA, IF et FACS.

Aperçu rapide pour STRADB anticorps (AA 24-411) (ABIN7872690)

Antigène: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STRADB est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-STRADB anticorps

Épitope: AA 24-411

Fonction: ILPIP Antibody / Als2Cr2

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids E24-E411) was used as the immunogen for the ILPIP antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the ILPIP antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the ILPIP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur STRADB

Antigène: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Autre désignation: ILPIP

Sujet: STE20-related kinase adapter protein beta, also called ILP-interacting protein (ILPIP) and Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein (Als2Cr2), is an enzyme that in humans is encoded by the STRADB gene. This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9C0K7

Pathways: AMPK Signaling