RP2 anticorps (AA 244-348)
Aperçu rapide pour RP2 anticorps (AA 244-348) (ABIN7872775)
Antigène
Voir toutes RP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 244-348
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Fonction
- RP2 Antibody
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Purification
- Affinity purified
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Immunogène
- A human recombinant protein (amino acids D244-M348) was used as the immunogen for the RP2 antibody.
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Isotype
- IgG2b
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Indications d'application
- Optimal dilution of the RP2 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the RP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))
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Autre désignation
- RP2
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Sujet
- Protein XRP2 is a protein that in humans is encoded by the RP2 gene. It is mapped to Xp11.3. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death.The RP2 protein is also involved in regulating the function and extension of outer segment of cone photoreceptors in mice.
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UniProt
- O75695
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Pathways
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
Antigène
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