PDE6B anticorps (AA 25-237)

N° du produit ABIN7872851

Cet anticorps Lapin Polyclonal détecte spécifiquement PDE6B dans WB, ELISA, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PDE6B anticorps (AA 25-237) (ABIN7872851)

Antigène: PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE6B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PDE6B anticorps

Épitope: AA 25-237

Fonction: PDE6 beta Antibody / PDE6B

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids K25-Q237) was used as the immunogen for the PDE6 beta antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PDE6 beta antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PDE6 beta antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PDE6B

Antigène: PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B))

Autre désignation: PDE6 beta

Sujet: Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P35913

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction