Recombinant IL-7 anticorps (AA 27-177)

N° du produit ABIN7873088

Cet anticorps Lapin Monoclonal détecte spécifiquement IL-7 dans FACS et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant IL-7 anticorps (AA 27-177) (ABIN7873088)

Antigène: IL-7 (IL7) (Interleukin 7 (IL7))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-7 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: IL7-7053R

Détail du produit anti-IL-7 anticorps

Épitope: AA 27-177

Fonction: Recombinant IL-7 Antibody

Purification: Protein A/G affinity

Immunogène: A recombinant fragment (within amino acids 27-177) corresponding to the mature human IL7 protein was used as the immunogen for the recombinant IL-7 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant IL-7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant IL-7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur IL-7

Antigène: IL-7 (IL7) (Interleukin 7 (IL7))

Autre désignation: IL-7

Sujet: Interleukin-7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene encodes a protein 177 amino acids in length. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor specific chain and the IL-2 receptor ? chain common to the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors. IL-7 stimulation leads to the activation of Janus tyrosine kinase family members JAK1 and JAK3. Other studies have shown that in T cells, the IL-7 receptor-specific chain associates with the Src kinases family Lck and Fyn. IL-7 induces phosphorylation of Insulin receptor substrate-1 (IRS-1) and Insulin receptor substrate-2 (IRS-2), originally called 4PS.

UniProt: P13232

Pathways: Signalistation JAK/STAT