FLT1 anticorps (AA 27-73)

N° du produit ABIN7873143

L’anticorps anti-FLT1 Polyclonal Lapin est utilisé pour la détection de FLT1 dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour FLT1 anticorps (AA 27-73) (ABIN7873143)

Antigène: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FLT1 anticorps

Épitope: AA 27-73

Fonction: VEGFR-1 Antibody / FLT1

Purification: Antigen affinity purified

Immunogène: An E.coli-derived human recombinant protein (amino acids S27-R73) was used as the immunogen for the VEGFR-1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the VEGFR-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the VEGFR-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur FLT1

Antigène: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Autre désignation: VEGFR-1

Sujet: Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

UniProt: P17948

Pathways: Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals