Recombinant IDH1 anticorps (AA 281-414)
Aperçu rapide pour Recombinant IDH1 anticorps (AA 281-414) (ABIN7873286)
Antigène
Voir toutes IDH1 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- AA 281-414
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Fonction
- IDH1 Antibody / Isocitrate Dehydrogenase (R132H mutant) (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- A portion of amino acids 281-414 was used as the immunogen for the IDH1 R132H antibody.
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Isotype
- IgG, kappa
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anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 1-414) antibody
IDH1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 74-333) antibodyIDH1 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 156-298) antibodyIDH1 Reactivité: Humain, Souris, Singe WB, ELISA, FACS, ICC Hôte: Souris Monoclonal 7G8A1 unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 116-143) antibodyIDH1 Reactivité: Humain, Souris WB, FACS, IF, IHC (p) Hôte: Lapin Polyclonal RB18238 unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 381-413), (C-Term) antibodyIDH1 Reactivité: Humain, Souris, Rat WB, IHC, FACS, IF, ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 156-298) antibodyIDH1 Reactivité: Humain, Souris, Singe WB, ELISA, FACS Hôte: Souris Monoclonal 4A4A8 unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (Center) antibodyIDH1 Reactivité: Humain, Souris WB, IP, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (N-Term) antibodyIDH1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 116-143) antibodyIDH1 Reactivité: Humain, Souris WB, IHC, ELISA, FACS, IF Hôte: Lapin Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1) (AA 63-90) antibodyIDH1 Reactivité: Humain, Souris WB, IHC, ELISA, FACS, IF Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal dilution of the IDH1 R132H antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the IDH1 R132H antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
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Autre désignation
- IDH1
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Sujet
- IDH1 R132H antibody binds to IDH1-mutated protein, but does not bind the wild-type IDH1 protein. IDH1 R132H point mutations are frequently seen in World Health Organization grade II and III gliomas and are believed to constitute an early step in tumorigenesis. IDH1 R132H can be used as a diagnostic marker to help differentiate infiltrating gliomas from gliosis, and as a prognostic marker for gliomas and secondary glioblastoma multiforme. IDH1 R132H antibody shows strong cytoplasmic staining and weaker nuclear staining in tumor cells with the R132H-mutated peptide. Diffuse staining of the fibrillary tumor matrix is also seen.
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UniProt
- O75874
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Pathways
- L'effet Warburg
Antigène
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