RORC anticorps (AA 286-511)
Aperçu rapide pour RORC anticorps (AA 286-511) (ABIN7873318)
Antigène
Voir toutes RORC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 286-511
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Fonction
- ROR gamma Antibody / RORC
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Purification
- Antigen affinity purified
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Immunogène
- Recombinant human protein (amino acids Q286-E511) was used as the immunogen for the ROR gamma antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the ROR gamma antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the ROR gamma antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RORC (RAR-Related Orphan Receptor C (RORC))
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Autre désignation
- ROR gamma
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Sujet
- RAR-related orphan receptor gamma (RORg) is a protein that in humans is encoded by the RORC (RAR-related orphan receptor C) gene. The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P51449
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
Antigène
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