SERBP1 anticorps (AA 3-139)

N° du produit ABIN7873491

L’anticorps anti-SERBP1 Monoclonal Souris est utilisé pour la détection de SERBP1 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour SERBP1 anticorps (AA 3-139) (ABIN7873491)

Antigène: SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SERBP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SERBP1-3509

Détail du produit anti-SERBP1 anticorps

Épitope: AA 3-139

Fonction: SERBP1 Antibody / PAI-RBP1

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 3-139 from the human protein was used as the immunogen for the SERBP1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the SERBP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the SERBP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur SERBP1

Antigène: SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))

Autre désignation: SERBP1

Sujet: SERBP1 is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, SERBP1 interacts with Mi2-s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer, suggesting a possible role in tumorigenesis and tumor metastasis.

UniProt: Q8NC51