TNNI2 anticorps (AA 3-182)

N° du produit ABIN7873521

L’anticorps anti-TNNI2 Polyclonal Lapin est utilisé pour la détection de TNNI2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF et IHC (p).

Aperçu rapide pour TNNI2 anticorps (AA 3-182) (ABIN7873521)

Antigène: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNI2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TNNI2 anticorps

Épitope: AA 3-182

Fonction: TNNI2 Antibody

Purification: Affinity purified

Immunogène: A human recombinant protein (amino acids D3-S182) was used as the immunogen for the TNNI2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the TNNI2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the TNNI2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur TNNI2

Antigène: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Autre désignation: TNNI2

Sujet: Troponin I, fast skeletal muscle is a protein that in humans is encoded by the TNNI2 gene. It is mapped to 11p15.5. This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

UniProt: P48788