Connexin 43/GJA1 anticorps (AA 3-362)

N° du produit ABIN7873539

L’anticorps anti-Connexin 43/GJA1 Polyclonal Lapin est utilisé pour la détection de Connexin 43/GJA1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF et IHC (p).

Aperçu rapide pour Connexin 43/GJA1 anticorps (AA 3-362) (ABIN7873539)

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Connexin 43/GJA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Connexin 43/GJA1 anticorps

Épitope: AA 3-362

Fonction: Connexin 43 Antibody

Purification: Affinity purified

Immunogène: A human recombinant protein (amino acids D3-R362) was used as the immunogen for the Connexin 43 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Connexin 43 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Connexin 43 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Connexin 43/GJA1

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Autre désignation: Connexin 43

Sujet: Connexin 43 (Cx43), also called GAP Junction Protein, alpha-1 (GJA1). Connexin 43 is a member of the connexin gene family which abundantly expressed in the heart and liver and was mapped to 6q21-q23.2. Connexin43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Mutations in the connexin 43 gap-junction gene, which lead to abnormally regulated cell-cell communication, are associated with visceroatrial heterotaxia. Cx43 must also play a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.

UniProt: P17302

Pathways: Signalisation MAPK, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization