Kallikrein 7 anticorps (AA 30-238)

N° du produit ABIN7873578

L’anticorps anti-Kallikrein 7 Polyclonal Lapin est utilisé pour la détection de Kallikrein 7 dans des échantillons de Rat. Il a été validé pour WB, ELISA et IHC (p).

Aperçu rapide pour Kallikrein 7 anticorps (AA 30-238) (ABIN7873578)

Antigène: Kallikrein 7 (KLK7)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Kallikrein 7 anticorps

Épitope: AA 30-238

Fonction: Kallikrein 7 Antibody / Klk7

Purification: Antigen affinity purified

Immunogène: An E.coli-derived rat recombinant protein (K30-N238) was used as the immunogen for the Kallikrein 7 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Kallikrein 7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Kallikrein 7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Kallikrein 7

Antigène: Kallikrein 7 (KLK7)

Autre désignation: Kallikrein 7

Sujet: Kallikrein-related peptidase 7 (KLK7) is a serine protease that in humans is encoded by the KLK7 gene. KLK7 is a chymotrypsin-like serine protease of the member of peptidase S1 family. It is synthesized with a signal peptide of 22 amino acids (aa 1-22) and a propeptide region (aa 23-29) that are subsequently cleaved to generate the mature form. Human KLK7 displays about 40 to 60 % amino acid homology with other members of the family. It cleaves proteins with aromatic side chains in the P1 position. KLK7 is abundantly expressed in the skin and is also present in the brain, mammary gland, cerebellum, spinal cord, and kidney. Lower levels of expression have been reported in in salivary glands, uterus, thymus, thyroid, placenta, trachea, and testis. Its levels are shown to be up-regulated in ovarian carcinoma, especially late-stage serous carcinoma. Less differentiated tumors of more advanced stage show higher level KLK7 expression. KLK7 activity is inhibited by zinc and copper ions

UniProt: P36373

Pathways: Système du Complément