LRRC47 anticorps (AA 309-583)

N° du produit ABIN7873742

Cet anticorps Lapin Polyclonal détecte spécifiquement LRRC47 dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour LRRC47 anticorps (AA 309-583) (ABIN7873742)

Antigène: LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC47 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-LRRC47 anticorps

Épitope: AA 309-583

Fonction: LRRC47 Antibody / Leucine-rich repeat-containing protein 47

Purification: Antigen affinity purified

Immunogène: An E.coli-derived human recombinant protein (amino acids L309-R583) was used as the immunogen for the LRRC47 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the LRRC47 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the LRRC47 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur LRRC47

Antigène: LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))

Autre désignation: LRRC47

Sujet: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

UniProt: Q8N1G4