LRRC47 anticorps (AA 309-583) (Fluoro550)

N° du produit ABIN8005526

Cet anticorps Lapin Polyclonal détecte spécifiquement LRRC47 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour LRRC47 anticorps (AA 309-583) (Fluoro550) (ABIN8005526)

Antigène: LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC47 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-LRRC47 anticorps (Fluoro550)

Épitope: AA 309-583

Fonction: Anti-LRRC47 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human LRRC47 recombinant protein (Position: L309-R583).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur LRRC47

Antigène: LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))

Autre désignation: LRRC47

Sujet:

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Gene Full Name: leucine rich repeat containing 47

ID gène: 57470

UniProt: Q8N1G4