Cytokeratin 5 anticorps (AA 318-491)

N° du produit ABIN7873899

L’anticorps anti-Cytokeratin 5 Monoclonal Souris est utilisé pour la détection de Cytokeratin 5 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Cytokeratin 5 anticorps (AA 318-491) (ABIN7873899)

Antigène: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 5 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KRT5-2080

Détail du produit anti-Cytokeratin 5 anticorps

Épitope: AA 318-491

Fonction: Cytokeratin 5 Antibody / KRT5

Purification: Culture supernatant

Immunogène: A recombinant human partial protein (amino acids 318-491) was used as the immunogen for this Cytokeratin 5 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Cytokeratin 5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Culture supernatant with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Cytokeratin 5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Cytokeratin 5

Antigène: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Autre désignation: Cytokeratin 5

Sujet: This MAb recognizes a protein of 58 kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium. Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express. Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5.

UniProt: P13647