CD82 anticorps (AA 32-266)

N° du produit ABIN7873913

Cet anticorps Lapin Polyclonal détecte spécifiquement CD82 dans ELISA, FACS et IHC (p). Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour CD82 anticorps (AA 32-266) (ABIN7873913)

Antigène: CD82

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD82 est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CD82 anticorps

Épitope: AA 32-266

Fonction: Cd82 Antibody

Purification: Affinity purified

Immunogène: Recombinant mouse protein (amino acids V32-Y266) was used as the immunogen for the Cd82 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Cd82 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Cd82 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CD82

Antigène: CD82

Autre désignation: Cd82

Sujet: CD82 (Cluster of Differentiation 82), also named KAI1, is a human protein encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma(ESCC). And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1.

UniProt: P40237

Pathways: Signalisation p53