T-Box 1 anticorps (AA 327-356)

N° du produit ABIN7873976

Cet anticorps Lapin Polyclonal détecte spécifiquement T-Box 1 dans WB, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour T-Box 1 anticorps (AA 327-356) (ABIN7873976)

Antigène: T-Box 1 (TBX1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp T-Box 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-T-Box 1 anticorps

Épitope: AA 327-356

Fonction: TBX1 Antibody / T-box protein 1

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 327-356 from the human protein was used as the immunogen for the TBX1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the TBX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the TBX1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur T-Box 1

Antigène: T-Box 1 (TBX1)

Autre désignation: TBX1

Sujet: TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UniProt: O43435

Pathways: Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation