MYCN anticorps (AA 335-463)

N° du produit ABIN7874046

L’anticorps anti-MYCN Monoclonal Souris est utilisé pour la détection de MYCN dans des échantillons de Humain. Il a été validé pour ELISA et FACS.

Aperçu rapide pour MYCN anticorps (AA 335-463) (ABIN7874046)

Antigène: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MYCN est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: PCRP-MYCN-1A9

Détail du produit anti-MYCN anticorps

Épitope: AA 335-463

Fonction: MYCN Antibody / n-Myc

Purification: Protein A/G affinity

Immunogène: A recombinant human MYCN protein (within amino acids 335-463) was used as the immunogen for the MYCN antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the MYCN antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MYCN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MYCN

Antigène: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Autre désignation: MYCN

Sujet: The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.

UniProt: P04198