RNLS anticorps (AA 34-235)

N° du produit ABIN7874066

Cet anticorps Souris Monoclonal détecte spécifiquement RNLS dans ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour RNLS anticorps (AA 34-235) (ABIN7874066)

Antigène: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RNLS est non-conjugé

Application: ELISA

Classe de qualité: Carrier-free

Clone: RNLS-1940

Détail du produit anti-RNLS anticorps

Épitope: AA 34-235

Fonction: Renalase Antibody (azide and preservative free)

Purification: Protein G affinity

Immunogène: A portion of amino acids 34-235 from the human protein was used as the immunogen for the Renalase antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Renalase antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Renalase antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur RNLS

Antigène: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Autre désignation: Renalase

Sujet: Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It is also suggested that Renalase functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. Individuals with chronic kidney disease and end-stage renal disease have markedly reduced levels of plasma Renalase than healthy individuals. Infusion of Renalase in animal models causes decrease in heart rate, cardiac contractility and blood pressure. Two isoforms of Renalase exist due to alternative splicing events.

UniProt: Q5VYX0