Recombinant FOXP1 anticorps (AA 350-450)

N° du produit ABIN7874194

Cet anticorps anti-FOXP1 Monoclonal Lapin (Clone FOXP1-9381R) (ABIN7874194) détecte spécifiquement FOXP1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant FOXP1 anticorps (AA 350-450) (ABIN7874194)

Antigène: FOXP1 (Forkhead Box P1 (FOXP1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp FOXP1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FOXP1-9381R

Détail du produit anti-FOXP1 anticorps

Épitope: AA 350-450

Fonction: FOXP1 Antibody / Forkhead box protein P1

Purification: Protein A/G affinity

Immunogène: A recombinant fragment (within amino acids 350-450) of human FOXP1 protein was used as the immunogen for the FOXP1 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the FOXP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the FOXP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur FOXP1

Antigène: FOXP1 (Forkhead Box P1 (FOXP1))

Autre désignation: FOXP1

Sujet: Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development. FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff (~80 % +) for FOXP1 is needed to achieve high specificity for the ABC subtype.

UniProt: Q9H334

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response