PDE12 anticorps (AA 36-607)

N° du produit ABIN7874325

L’anticorps anti-PDE12 Polyclonal Lapin est utilisé pour la détection de PDE12 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour PDE12 anticorps (AA 36-607) (ABIN7874325)

Antigène: PDE12 (Phosphodiesterase 12 (PDE12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE12 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-PDE12 anticorps

Épitope: AA 36-607

Fonction: PDE12 Antibody / Mitochondrial deadenylase / 2',5'-phosphodiesterase 12

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived human recombinant protein (amino acids E36-K607) was used as the immunogen for the PDE12 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PDE12 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PDE12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PDE12

Antigène: PDE12 (Phosphodiesterase 12 (PDE12))

Autre désignation: PDE12

Sujet: PDE12 is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. It also cleaves 3',5'-phosphodiester bond of oligoadenylates and plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.

UniProt: Q6L8Q7