ZNF202 anticorps (AA 37-132)

N° du produit ABIN7874391

L’anticorps anti-ZNF202 Monoclonal Souris est utilisé pour la détection de ZNF202 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour ZNF202 anticorps (AA 37-132) (ABIN7874391)

Antigène: ZNF202 (Zinc Finger Protein 202 (ZNF202))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ZNF202 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: PCRP-ZNF202-1C4

Détail du produit anti-ZNF202 anticorps

Épitope: AA 37-132

Fonction: ZNF202 Antibody

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein (within amino acids 37-132) from the human protein was used as the immunogen for the ZNF202 antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the ZNF202 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ZNF202 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ZNF202

Antigène: ZNF202 (Zinc Finger Protein 202 (ZNF202))

Autre désignation: ZNF202

Sujet: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF202 (zinc finger protein 202), also known as ZKSCAN10, is a 648 amino acid protein that contains eight C2H2-type zinc fingers, one KRAB domain and one SCAN box domain. Localized to the nucleus and expressed at high levels in the testis, ZNF202 belongs to the Kruppel C2H2-type zincfinger protein family and functions as a transcriptional repressor of genes that are involved in lipid metabolism. ZNF202 regulates the expression of several classes of proteins, including lipoprotein particles, transporters involved in lipid homeostasis, enzymes involved in lipid processing and a wide variety of proteins that are associated with energy metabolism. Defects in the gene encoding ZNF202 are associated with high cholesterol and may be involved in the pathogenesis of lung, ovarian and breast cancer. Two isoforms of ZNF202, designated a and b, exist due to alternative splicing events

UniProt: O95125