PKM anticorps (AA 383-417)

N° du produit ABIN7874526

L’anticorps anti-PKM Polyclonal Lapin est utilisé pour la détection de PKM dans des échantillons de Humain. Il a été validé pour WB, FACS et IHC (p).

Aperçu rapide pour PKM anticorps (AA 383-417) (ABIN7874526)

Antigène: PKM (Pyruvate Kinase M1/2 (PKM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKM est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PKM anticorps

Épitope: AA 383-417

Fonction: Pyruvate Kinase PKM Antibody / PKM2

Purification: Purified

Immunogène: A portion of amino acids 383-417 from the human protein was used as the immunogen for the Pyruvate Kinase PKM antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Pyruvate Kinase PKM antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Pyruvate Kinase PKM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PKM

Antigène: PKM (Pyruvate Kinase M1/2 (PKM))

Autre désignation: Pyruvate Kinase PKM

Sujet: PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

UniProt: P14618

Pathways: L'effet Warburg