Myosin VI anticorps (AA 383-786)
Aperçu rapide pour Myosin VI anticorps (AA 383-786) (ABIN7874533)
Antigène
Voir toutes Myosin VI (MYO6) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 383-786
-
Fonction
- MYO6 Antibody / Unconventional Myosin-6
-
Purification
- Antigen affinity purified
-
Immunogène
- An E.coli-derived human recombinant protein (Q383-H786) was used as the immunogen for the MYO6 antibody.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal dilution of the MYO6 antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- After reconstitution, the MYO6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Myosin VI (MYO6)
-
Autre désignation
- MYO6
-
Sujet
- Unconventional myosin-VI, is a protein that in humans is coded for by MYO6. This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
-
UniProt
- Q9UM54
-
Pathways
- Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization
Antigène
-