Recombinant STAR anticorps (AA 39-108)

N° du produit ABIN7874557

Cet anticorps anti-STAR Monoclonal Lapin (Clone STAR-3915R) (ABIN7874557) détecte spécifiquement STAR dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant STAR anticorps (AA 39-108) (ABIN7874557)

Antigène: STAR (Steroidogenic Acute Regulatory Protein (STAR))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp STAR est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: STAR-3915R

Détail du produit anti-STAR anticorps

Épitope: AA 39-108

Fonction: Recombinant StAR Antibody / Steroidogenic acute regulatory protein (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 39-108 was used as the immunogen for the recombinant StAR antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant StAR antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant StAR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur STAR

Antigène: STAR (Steroidogenic Acute Regulatory Protein (STAR))

Autre désignation: StAR

Sujet: Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone.It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.

UniProt: P49675

Pathways: Metabolism of Steroid Hormones and Vitamin D, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis