BCL9L anticorps (AA 397-666)

N° du produit ABIN7874649

L’anticorps anti-BCL9L Polyclonal Lapin est utilisé pour la détection de BCL9L dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF et IHC (p).

Aperçu rapide pour BCL9L anticorps (AA 397-666) (ABIN7874649)

Antigène: BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL9L est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BCL9L anticorps

Épitope: AA 397-666

Fonction: BCL9L Antibody

Purification: Affinity purified

Immunogène: Amino acids E397-A666 from the human protein were used as the immunogen for the BCL9L antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the BCL9L antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: Store the BCL9L antibody at -20oC.

Détails sur BCL9L

Antigène: BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))

Autre désignation: BCL9L

Sujet: B-cell CLL/lymphoma 9 like is a protein that in humans is encoded by the BCL9L gene. It is mapped to 11q23.3. Bcl-9 (B-cell lymphoma 9, also Protein legless homolog) is a transcriptional regulator that belongs to the Bcl-9 family of proteins. It is expressed in multiple tissues and serves to recruit Pygopus to the Wnt-pathway beta -catenin-TCF complex in the nucleus. Bcl-9 and Bcl-9-2 are considered evolutionary duplicates of Legless that perform the same task with different regulation. Human Bcl-9 is 1426 amino acids (aa) in length. It contains one phosphothreonine and three phosphoserine sites that have been identified so far, two poly-Pro regions (aa 514?517 and 970?973), and one poly-Ala segment (aa 900?903). There is one potential alternate start site at Met27, and a variant isoform exists that shows a four aa substitution for aa 1391?1426. Over aa 1009?1328, human Bcl-9 is 96 % aa identical to mouse Bcl-9.

UniProt: Q86UU0

Pathways: Stem Cell Maintenance