MED17 anticorps (AA 4-561)
Aperçu rapide pour MED17 anticorps (AA 4-561) (ABIN7874682)
Antigène
Voir toutes MED17 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 4-561
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Fonction
- MED17 Antibody / Trap80 / ARC77
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived human recombinant protein (V4-E561) was used as the immunogen for the MED17 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the MED17 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the MED17 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MED17 (Mediator Complex Subunit 17 (MED17))
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Autre désignation
- MED17
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Sujet
- Mediator of RNA polymerase II transcription subunit 17 is an enzyme that in humans is encoded by the MED17 gene. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
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UniProt
- Q9NVC6
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Antigène
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