GIT2 anticorps (AA 400-556)

N° du produit ABIN7874728

Cet anticorps anti-GIT2 Polyclonal Lapin (ABIN7874728) détecte spécifiquement GIT2 dans WB, ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour GIT2 anticorps (AA 400-556) (ABIN7874728)

Antigène: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GIT2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-GIT2 anticorps

Épitope: AA 400-556

Fonction: GIT2 Antibody / GRK-interacting protein 2

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids D400-S556) was used as the immunogen for the GIT2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the GIT2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the GIT2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur GIT2

Antigène: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Autre désignation: GIT2

Sujet: ARF GTPase-activating protein GIT2 is an enzyme that in humans is encoded by the GIT2 gene. This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding.

UniProt: Q14161

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling