MMP2 anticorps (AA 412-573)

N° du produit ABIN7874864

Cet anticorps Lapin Polyclonal détecte spécifiquement MMP2 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MMP2 anticorps (AA 412-573) (ABIN7874864)

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MMP2 anticorps

Épitope: AA 412-573

Fonction: Matrix metalloproteinase 2 Antibody / MMP2

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids E412-N573) was used as the immunogen for the Matrix metalloproteinase 2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Matrix metalloproteinase 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Matrix metalloproteinase 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MMP2

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Autre désignation: Matrix metalloproteinase 2

Sujet: Matrix metalloproteinase-2 (MMP2) is a Type IV collagenase, 72-kD, which is also known as gelatinase and is a member of a group of secreted zinc metalloproteases. The MMP2 gene is 17 kb long with 13 exons varying in size from 110 to 901 bp and 12 introns ranging from 175 to 4,350 bp, located within a region of human chromosome 16q13. In addition, the extra exons encode the amino acids of the fibronectin-like domain which has so far been found in only the 72- and 92- kDa type IV collagenase. MMP2, which has a critical role in the binding of progelatinase A and TIMP4 via the C-terminal hemopexin-like domain (C domain), is functionally associated on the surface of angiogenic blood vessels. Not only is a likely effector of endometrial menstrual breakdown, MMP2 is also effector and regulator of the inflammatory response. Moreover, MMP2 could be helpful in diagnosing Takayasu arteritis.

UniProt: P08253

Pathways: Activation of Innate immune Response