Transglutaminase 2 anticorps (AA 429-458)

N° du produit ABIN7874943

L’anticorps anti-Transglutaminase 2 Polyclonal Lapin est utilisé pour la détection de Transglutaminase 2 dans des échantillons de Humain. Il a été validé pour WB, IF et IHC (p).

Aperçu rapide pour Transglutaminase 2 anticorps (AA 429-458) (ABIN7874943)

Antigène: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transglutaminase 2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Transglutaminase 2 anticorps

Épitope: AA 429-458

Fonction: Protein-glutamine gamma-glutamyltransferase 2 Antibody / Transglutaminase 2

Purification: Purified

Immunogène: A portion of amino acids 429-458 from the human protein was used as the immunogen for the Protein-glutamine gamma-glutamyltransferase 2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Protein-glutamine gamma-glutamyltransferase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Protein-glutamine gamma-glutamyltransferase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Transglutaminase 2

Antigène: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Autre désignation: Protein-glutamine gamma-glutamyltransferase 2

Sujet: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.

UniProt: P21980

Pathways: Tube Formation, Thromboxane A2 Receptor Signaling