Metabotropic Glutamate Receptor 5 anticorps (AA 443-1050)

N° du produit ABIN7875037

Cet anticorps anti-Metabotropic Glutamate Receptor 5 Polyclonal Lapin (ABIN7875037) détecte spécifiquement Metabotropic Glutamate Receptor 5 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Rat et Humain.

Aperçu rapide pour Metabotropic Glutamate Receptor 5 anticorps (AA 443-1050) (ABIN7875037)

Antigène: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Reactivité: Rat, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Metabotropic Glutamate Receptor 5 anticorps

Épitope: AA 443-1050

Fonction: mGluR5 Antibody / Glutamate Metabotropic Receptor 5 / GRM5

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids K443-S1050) was used as the immunogen for the mGluR5 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the mGluR5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the mGluR5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Metabotropic Glutamate Receptor 5

Antigène: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Autre désignation: mGluR5

Sujet: Metabotropic glutamate receptor 5 is a G protein-coupled receptor that in humans is encoded by the GRM5 gene. It is mapped to 11q14.2-q14.3. This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.

UniProt: P41594

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity