MEFV anticorps (AA 463-781)

N° du produit ABIN7875136

Cet anticorps anti-MEFV Polyclonal Lapin (ABIN7875136) détecte spécifiquement MEFV dans WB, ELISA, IF, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour MEFV anticorps (AA 463-781) (ABIN7875136)

Antigène: MEFV (Mediterranean Fever (MEFV))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEFV est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MEFV anticorps

Épitope: AA 463-781

Fonction: Pyrin Antibody / Marenostrin / MEFV

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids Q463-D781) was used as the immunogen for the Pyrin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Pyrin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Pyrin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MEFV

Antigène: MEFV (Mediterranean Fever (MEFV))

Autre désignation: Pyrin

Sujet: MEFV (Mediterranean fever) is a human gene that provides instructions for making a protein called pyrin (also known as marenostrin). Pyrin is produced in certain white blood cells (neutrophils, eosinophils and monocytes) that play a role in inflammation and in fighting infection. Inside these white blood cells, pyrin is found with thecytoskeleton, the structural framework that helps to define the shape, size, and movement of a cell. Pyrin's protein structure also allows it to interact with other molecules involved in fighting infection and in the inflammatory response. Although pyrin's function is not fully understood, it likely assists in keeping the inflammation process under control. Research indicates that pyrin helps regulate inflammation by interacting with the cytoskeleton. And Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed.

UniProt: O15553

Pathways: Positive Regulation of Endopeptidase Activity