L’anticorps anti-Fibronectin 1 Monoclonal Souris est utilisé pour la détection de Fibronectin 1 dans des échantillons de Humain. Il a été validé pour ELISA et IHC (p).
Optimal dilution of the FN1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
4 °C,-20 °C
Stockage commentaire
Store the FN1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Antigène
Fibronectin 1 (FN1)
Autre désignation
FN1
Sujet
Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin.