SCARB2 anticorps (AA 48-357)

N° du produit ABIN7875206

Cet anticorps Lapin Polyclonal détecte spécifiquement SCARB2 dans WB, ELISA, IHC (p), FACS et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SCARB2 anticorps (AA 48-357) (ABIN7875206)

Antigène: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCARB2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-SCARB2 anticorps

Épitope: AA 48-357

Fonction: SR-BII Antibody / SCARB2 / LIMPII

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids E48-H357) was used as the immunogen for the SR-BII antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SR-BII antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the SR-BII antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SCARB2

Antigène: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Autre désignation: SR-BII

Sujet: Lysosomal integral membrane protein 2 (LIMP-2), also called Scavenger receptor class B member 2, is a protein that in humans is encoded by the SCARB2 gene. The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q14108