KIF3A anticorps (AA 486-701)

N° du produit ABIN7875231

L’anticorps anti-KIF3A Polyclonal Lapin est utilisé pour la détection de KIF3A dans des échantillons de Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour KIF3A anticorps (AA 486-701) (ABIN7875231)

Antigène: KIF3A (Kinesin Family Member 3A (KIF3A))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF3A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KIF3A anticorps

Épitope: AA 486-701

Fonction: Zebrafish Kif3a Antibody

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived zebrafish Kif3a recombinant protein (amino acids D486-Q701) was used as the immunogen for the Zebrafish Kif3a antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Kif3a antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Kif3a antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur KIF3A

Antigène: KIF3A (Kinesin Family Member 3A (KIF3A))

Autre désignation: Kif3a

Sujet: Kinesin-like protein KIF3A is a protein that in humans is encoded by the KIF3A gene. KIF3A is one subunit of the heterotrimeric motor protein, kinesin-2, that was initially isolated from sea urchin egg/embryo cytosol using microtubule affinity purification. This motor consists of two kinesin-related subunits (called KIF3A and KIF3B or 3C in vertebrates) and an associated protein (KAP3), and it transports protein complexes, nucleic acids and organelles towards the plus ends of microtubule tracks within cells. Work done in a broad range of eukaryotic cells has revealed that heterotrimeric kinesin-2 is the primary motor protein driving the intra-flagellar transport of tubulins and other axonemal building blocks from the base of the ciliary/flagellar axoneme to their site of assembly at the distal tips. This process is required for cilium assembly/maintenance and cilium-based signalling which play key roles in various cell and developmental processes. For example, in vertebrate embryos, kinesin-2 function is required for cilia-dependent nodal flow and the development of left-right asymmetry.

UniProt: E9QB71

Pathways: Signalisation Hedgehog