Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 498-804) anticorps

N° du produit ABIN7875284

Cet anticorps Lapin Polyclonal détecte spécifiquement Protocadherin gamma Subfamily C, 3 dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 498-804) anticorps (ABIN7875284)

Antigène: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit

Épitope: AA 498-804

Fonction: PCDHGC3 Antibody / Protocadherin gamma C3

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived human recombinant protein (amino acids E498-E804) was used as the immunogen for the PCDHGC3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PCDHGC3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PCDHGC3 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détail du antigène

Antigène: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Autre désignation: PCDHGC3

Sujet: Protocadherin gamma-C3 is a protein that in humans is encoded by the PCDHGC3 gene. This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

UniProt: Q9UN70