Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 518-547), (Middle Region) anticorps

N° du produit ABIN954050

Détail du produit

Antigène: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Épitope: AA 518-547, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes PCDHGC3.

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the central region (between 518-547aa) of human PCDHGC3.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détail du antigène

Antigène: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Autre désignation: PCDHGC3 (PCDHGC3 Produits)

Synonymes: anticorps PC43, anticorps PCDH-GAMMA-C3, anticorps PCDH2, anticorps Pcdh2, anticorps PCDHGA11, anticorps PCDHGC5, anticorps protocadherin gamma subfamily C, 3, anticorps PCDHGC3, anticorps Pcdhgc3

Sujet: The PCDHGC3 gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.Synonyms: PC-43, PC43, PCDH-gamma-C3, PCDH2, Protocadherin 2, Protocadherin 43, Protocadherin gamma-C3, Protocadherin-2, Protocadherin-43

Poids moléculaire: 101077 Da

ID gène: 5098

NCBI Accession: NP_002579