Peroxiredoxin 2 anticorps (AA 5-127)

N° du produit ABIN7875288

L’anticorps anti-Peroxiredoxin 2 Polyclonal Lapin est utilisé pour la détection de Peroxiredoxin 2 dans des échantillons de Humain. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour Peroxiredoxin 2 anticorps (AA 5-127) (ABIN7875288)

Antigène: Peroxiredoxin 2 (PRDX2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Peroxiredoxin 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-Peroxiredoxin 2 anticorps

Épitope: AA 5-127

Fonction: PRDX2 Antibody / Peroxiredoxin 2

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids N5-R127) was used as the immunogen for the PRDX2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PRDX2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PRDX2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Peroxiredoxin 2

Antigène: Peroxiredoxin 2 (PRDX2)

Autre désignation: PRDX2

Sujet: PRDX2 (Peroxiredoxin 2) also known as NKEFB, PRP, PRX2, PRXII or TPX1, is a protein that in humans is encoded by the PRDX2 gene. This gene encodes a member of the peroxiredoxin family of anti-oxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The Prdx2-/- mice were healthy in appearance and fertile. Choi et al.(2005) demonstrated that PRDX2 is a negative regulator of PDGF signaling. Prx II deficiency results in increased production of peroxide, enhanced activation of PDGF receptor and phospholipase C-gamma-1, and subsequently increased cell proliferation and migration in response to PDGF. PRX2 accounted for about half of the thioredoxin activity in parasite extracts, and PRX2 expression was increased in the presence of chloroquine, regardless of P. falciparum strain susceptibility to the drug.

UniProt: P32119