SOX18 anticorps (AA 50-250)

N° du produit ABIN7875394

Cet anticorps anti-SOX18 Monoclonal Souris (Clone SOX18-3271) (ABIN7875394) détecte spécifiquement SOX18 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SOX18 anticorps (AA 50-250) (ABIN7875394)

Antigène: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOX18 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SOX18-3271

Détail du produit anti-SOX18 anticorps

Épitope: AA 50-250

Fonction: SOX18 Antibody

Purification: Protein A/G affinity

Immunogène: A recombinant human SOX18 protein fragment (within amino acids 50-250) was used as the immunogen for the SOX18 antibody.

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal dilution of the SOX18 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SOX18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SOX18

Antigène: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Autre désignation: SOX18

Sujet: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNAbinding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Sox-18 is a 384 amino acid nuclear protein that contains one HMG box DNA-binding domain and belongs to the Sox family of transcriptional regulators.

UniProt: P35713