Dysferlin anticorps (AA 51-747)

N° du produit ABIN7875526

Cet anticorps anti-Dysferlin Polyclonal Lapin (ABIN7875526) détecte spécifiquement Dysferlin dans WB, ELISA, IF, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Dysferlin anticorps (AA 51-747) (ABIN7875526)

Antigène: Dysferlin (DYSF)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dysferlin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Dysferlin anticorps

Épitope: AA 51-747

Fonction: DYSF Antibody / Dysferlin

Purification: Affinity purified

Immunogène: An E. coli-derived human protein (amino acids E51-H747) was used as the immunogen for the DYSF antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the DYSF antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the DYSF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Dysferlin

Antigène: Dysferlin (DYSF)

Autre désignation: DYSF

Sujet: Dysferlin also known as dystrophy-associated fer-1-like protein is a protein that in humans is encoded by the DYSF gene. The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants.

UniProt: O75923