PLA2G1B anticorps (AA 513-541)

N° du produit ABIN7875533

Cet anticorps Lapin Polyclonal détecte spécifiquement PLA2G1B dans WB, IF, FACS et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PLA2G1B anticorps (AA 513-541) (ABIN7875533)

Antigène: PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLA2G1B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PLA2G1B anticorps

Épitope: AA 513-541

Fonction: Phospholipase A2 Antibody / PLA2G4A / cPLA2

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 513-541 from the human protein was used as the immunogen for the Phospholipase A2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Phospholipase A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Phospholipase A2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PLA2G1B

Antigène: PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Autre désignation: Phospholipase A2

Sujet: PLA2G4A is a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

UniProt: P47712

Pathways: Inositol Metabolic Process, VEGF Signaling