Neuropilin 1 anticorps (AA 521-827)
Aperçu rapide pour Neuropilin 1 anticorps (AA 521-827) (ABIN7875582)
Antigène
Voir toutes Neuropilin 1 (NRP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 521-827
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Fonction
- Neuropilin 1 Antibody / NRP1
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived human recombinant protein (amino acids N521-T827) was used as the immunogen for the Neuropilin 1 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Neuropilin 1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Neuropilin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Neuropilin 1 (NRP1)
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Autre désignation
- Neuropilin 1
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Sujet
- This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
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UniProt
- O14786
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Pathways
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
Antigène
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